P 364
Correlation of retrobulbar color doppler imaging with retinal Scanning Laser Fluorescein Angiography
K. Huber, O. Arend, R. Gnielinski, A. Remky, A. Harris
Purpose: To understand how retinal circulatory measurements using scanning laser fluorescein angiography relate to retrobulbar flow velocities using color Doppler imaging.
Methods: Thirty one patients with normal pressure glaucoma underwent color Doppler imaging (Siemens Quantum 2000) and fluorescein angiographic studies (SLO Rodenstock). Peak systolic, end-diastolic velocities (EDV) and resistive index (RI) of the ophthalmic artery, central retinal artery and the short ciliary arteries were obtained. In the fluorescein angiograms by means of dye curve analysis arteriovenous passage (AVP) times and mean dye velocities (MDV) were quantified.
Results: The end-diastolic velocity and the resistive index of the central retinal artery showed a significant correlation with AVP (EDV:r=-0.32, p<0.05; RI: r=0.33, p<0.05). All other measurements of the retrobulbar vasculature were unrelated to the angiographic measures.
Conclusion: The combined approach of fluorescein angiographic and color Doppler studies showed that AVP changes are correlated with resistive indices and end-diastolic velocity measurements of the central retinal artery. AVP representing a vascular segment of artery, capillary bed and corresponding vein seems dependent on resistance changes. Retinal arterial velocity changes alone (MDV) are not associated with resistance changes underlining the importance of the capillary bed for resistance regulations.
Dept. of Ophthalmology, Indiana University, Indianapolis, IN, USA
Augenklinik der RWTH-Aachen, Pauwelsstrasse 30, 52057 Aachen