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Impressum
Corneal endothelial coating of dispersive and cohesive viscoelastics: An experimental laboratory study
1Auffarth G. U., 2Peng Q., 1Becker K. A., 2Apple D. J., 1Völcker H. E.
1Univ.-Augenklinik Heidelberg, INF 400, 69120 Heidelberg; 2Center for Research on Ocular Therapeutics and Biodevices, Charleston, USA
Purpose: Dispersive and cohesive viscoelastic substances differ
fundamentally by their physical and bio-chemical behaviour.
Methods: In a standardised experimental laboratory study using
human cadaver eyes the retention of flourescein stained Viscoat® (=dispersive)
and Pro Visc® (=cohesive) were investigated in the anterior chamber
during phacoemulsification using the Closed System Technique as described
by Auffarth et al. After the phacoemulsification was finished the corneas
were trephined and the endothelial coating with Viscoat®/ProVisc®
was quantified with a image analysis program.
Results: The mean endothelial cover using Viscoat® was 43,9
± 16,9% of the posterior corneal endothelial surface area, using
Pro Visc® 2,2% and by combining of both viscoelastics 55,0 ±
3,9% using the Soft Shell Technique.
Conclusions: The dispersive Viscoat showed a very good endothelial
protection during the whole procedure of phacoemulsification.