Abstract 99. Jahrestagung der DOG, 29. 9. - 2. 10. 01 im ICC, Berlin

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Neuronal control of the intraocular pressure

Erb C.

Medizinische Hochschule Hannover, Department of Ophthalmology, Carl-Neuberg-Str. 1, D-30625 Hannover

Intraocular pressure (IOP) is one of the main risk factors for the development of an glaucomatous optic neuropathy. Therefore understanding of the regulation of the IOP is of substantial interest. At first previous knowledge about fine regulation of the IOP will be presented, like the supply of different nerve fibers to ciliary body and trabecular meshwork, and the influence of neurotransmitters on the secretion of aqueous humor and the tone of tension of the trabecular meshwork. In the second part, the importance of this knowledge is transferred to the clinical aspects of the primary open angle glaucoma, for example the daily IOP-amplitudes of about 15 mm Hg, and at the same time the disturbance of other neuronal triggered circuits, like the autoregulation of the optic nerve or the regulation of the blood pressure.




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