Abstract 99. Jahrestagung der DOG, 29. 9. - 2. 10. 01 im ICC, Berlin

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Funduscopic, fluorescein and indiocyanine green angiographic findings of chorioretinal changes in subacute sclerosing panencephalitis (SSEP).

Floegel I., El-Shabrawi Y., Haas A.

Universitäts-Augenklinik Graz, Österreich

Purpose: Funduscopic, fluorescein- and ICG-angiographic findings of chorioretinal changes in subacute sclerosing panencephalitis (SSEP) (=measles slow virus encephalitis) are reported.
Methods: Case report and a review of literature
Results: A 21-year-old women presented with a profound loss of vision in the left eye. The initial clinical picture was characterized by a whitish retinal infiltration with small retinal haemorrhage in the macular area and papillary oedema. Six days later multiple retinal infiltrations followed in the peripheral fundus. The patient was started on antiviral therapy and within the next weeks the lesions faded away leaving behind pigmented scars. During the following year, a graduate change in her personality has been noted, associated with a deterioration in her intellect. The diagnosis of SSEP was made by cerebrospinal fluid examination. Her clinical condition deteriorated and she died.
Conclusion: Funduscopic and angiographic features of chorioretinitis due to SSPE are reported. Differential diagnostic considerations are explained. We wish to emphasise the importance of thinking of SSPE or other slow virus infections of the brain in cases of chorioretinitis. The diagnoses can only be made by spinal fluid examination.




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