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Impressum
Brinzolamid eye drops 1% for Nd:YAG laser capsulotomy
Groeschel W., Weindler J.
Augen-Praxisklinik, Neckarstr. 71, 73728 Esslingen
Purpose: To compare the effect of Brinzolamid 1% (AZOPT®)
and placebo eye drops on the inflammatory reaction and the intraocular
pressure after Nd:YAG laser capsulotomy.
Methods: This prospective, randomized and double-blind study compared
2 groups of up to now 20 eyes each undergoing Nd:YAG laser capsulotomy
( ZEISS VisuLas YAG II plus ). Group A was treated with Brinzolamid 1%
and group B was treated with placebo each 30 minutes before capsulotomy.
The intraocular pressure is measured by applanation tonometry and postoperative
inflammation by KOWA Laser-Flare-Meter FM-500 pre as well as 3 and 24
hours post Nd:YAG laser capsulotomy.
Results: Group B (placebo) showed neither an increase nor a decrease
of intraocular pressure after capsulotomy. Group A (Brinzolamid 1%) showed
a significant intraocular pressure decrease 3 hours after Nd:YAG laser
capsulotomy. The group receiving placebo showed a significant increase
of laser flare 3 hours postoperatively. The group receiving Brinzolamid
1% showed no significant changes in laser flare.
Conclusion: Brinzolamid 1% eye drops seems to be sure to decrease
intraocular pressure while not sure to be affecting postoperative inflammatory
reaction in normal (no-risk) eyes undergoing Nd:YAG laser capsulotomy.
Brinzolamid-Augentropfen 1% zur Nd:YAG-Kapsulotomie.