Anmeldung zur Tagung
Registration
Grußwort
Invitation
Themen
Topics
Allgemeiner Ablauf
General overview
Wissenschaftliches Programm
Scientific program
Kurse
Courses
Symposien
Symposiums
Frühstück mit Spezialisten
Breakfast with specialists
Arzthelferinnen-Fortbildung
Rahmenprogramm
Social program
DOG Information
DOG Information
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Ausstellerliste
Exhibitors
Sponsoren
Sponsors
Teilnahmegebühren
Registration fees
Impressum
Corneal curvature and thickness in patients with ocular hypertension, primary open angle glaucoma and healthy subjects
Hayler J. K., Ferreira de Souza R., Langenbucher A., Seitz B.
Dept. of Ophthalmology Univ. Erlangen-Nürnberg, Erlangen
Purpose: To investigate the anterior and posterior corneal curvature
in eyes with ocular hypertension (OHT), primary open angle glaucoma (POAG)
and healthy subjects (N) and to compare the corneal thickness results
by optical and ultrasonic measurements.
Method: 138 OHT and 44 POAG and 44 N of the Erlanger Glaukomregister
were consecutively examined by Orbscan Slit-Scanning-Topographie (SST)
and ultrasound pachymetry (mean of three measurements). Main outcome measures
included anterior and posterior corneal curvature, thickness of the cornea
centrally and at the midperipheral superior, inferior, nasal and temporal
area. Mean value of the ultrasonic central corneal thickness was compared
to central thickness measured by SST.
Results: The posterior corneal curvature was not significantly
different between groups. Anterior corneal power was significantly increased
in OHT (48.7±2.4 Diopter=D; p=0.03) and POAG (48.8±2.2 D;
p=0.03) compared to N (47.9± 2.2 D). Central optical pachymetry
was 14.4±39.9 mm thicker than ultrasonic pachymetry (p<0.01).
Central optical pachymetry was significantly higher in OHT vs. N (p=0.03)
and vs. POAG (p=0.01) and higher in OHT vs. POAG midperipheral: superior
(p=0.01); temporal (p=0.06); inferior (p=0.04); nasal (p<0.01). Comparing
POAG vs. N corneal thickness was significantly thinner in POAG in the
midperipheral nasal (p<0.01) and superior (p< 0.01) area.
Conclusion: Generally optical pachymetry results in greater thickness
values than ultrasonic pachymetry. Increased corneal thickness in OHT
vs. N and POAG was reconfirmed. The importance of anterior compared to
the posterior corneal curvature for differentiation of normals and various
types of glaucoma needs further investigation.
Supported by DFG, SFB 539