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Impressum
Optic nerve head screening with confocal laser scanning tomography in healthy adults
Hermann M. M., Theofylaktopoulos I., Jonescu-Cuypers C. P., Bangard N., Diestelhorst M.
Augenklinik, Universität zu Köln
Purpose: To investigate the optic nerve head characteristics of
a healthy population in a cross-sectional study as measured by confocal
laser scanning tomography.
Methods: Adults with no history of glaucoma, ocular hypertension
or other ocular pathology were eligible for the study. The examination
included assessment of visual acuity, slitlamp examination of the anterior
and posterior segment, Goldmann applanation tonometry, computerized perimetry,
optic nerve head tomography with Heidelberg Retina Tomograph. Eyes with
ocular hypertension, glaucoma, papilla leporina, papilledema or tilted
disc were excluded. Micro- and macropapillae were included. Mean, standard-deviation
and OD-OS were calculated for disc area, cup area, cup/disc area ratio,
rim area, mean RNFLT and rim volume. Differences in age-quartiles and
gender were explored.
Results: We included 1764 eyes of 882 patients (154 female and
728 male; mean age: 46.8±8.6 years). We found no significant differences
in gender. For mean RNFLT and rim volume we found significant differences
between OD and OS (p<0.001).
Conclusions: Our findings confirm earlier studies in our clinic
in younger healthy volunteers. According to our findings in this large
population we propose a definition for micro- and macro-papillae for HRT
measurements.