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Impressum
Clinical outcome after Early Vitrectomy in Proliferative Diabetic Vitreoretinopathy (PDVR)
Jentzmik P. N., Gümbel H. O. C., Koch F. H. J., Hattenbach L. O.
Klinik für Augenheilkunde, Netzhaut- und Glaskörperchirurgie, Klinikum der Johann Wolfgang Goethe Universität, D-60590 Frankfurt am Main
Objective: To investigate visual recovery and clinical outcome
after early vitrectomy in patients with PDVR.
Methods: Fourty-nine eyes of 40 patients with PDVR and severe visual
loss were included in this prospective study. The average age by the time
of surgery was 62.2 years (range 38-86 years). The duration of diabetes
mellitus by the time of surgery ranged from 2 to 43 years (mean 21.6 yrs).
Minimum follow-up time was 6 months (range 6 to 37 months).
Results: By the end of the follow-up period, visual acuity was
improved 2 or more lines in 18 of 49 eyes (36.7%), 3 or more lines in
13 of 49 eyes (26.5%), and 6 or more lines in 10 of 49 eyes (20.4%), respectively.
In 22 of 49 eyes (44.9%), final visual acuity remained unchanged (change
< 2 lines). A further decrease in visual acuity was observed in 9 eyes
(18.4%). Overall, visual acuity was improved or stable in 40 of 49 cases
(81.6%). In 3 of 49 eyes, severe vitreous hemorrhage occurred within a
period of 4 weeks. Repeat vitrectomy was performed in 2 of 49 eyes.
Discussion: Our findings suggest that early vitrectomy is of value
for an improved visual recovery in patients with PDVR. Moreover, the progression
rate of PDVR after early surgical treatment appears to be low.