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Impressum
Effect of External Trabecular Excision (ETE) on ocular hemodynamics
Kuba G. B., Austermann-Schmidt P., Schmidt J., Kroll P.
Augenheilklinik der Philipps-Universität Marburg, Robert Koch Str. 4, D- 35037 Marburg
Purpose: External Trabecular Excision (ETE) lowers sufficiently
intraocular pressure. However, the effect of this new operation method
on ocular hemodynamics is not jet known.
Methods: 25 eyes of 21 consecutive glaucoma patients ( primary
open angle glaucoma 13, low tension glaucoma 3, PEX glaucoma 4, pigmentary
glaucoma 1; 10 females, 11 males; mean age 67,29 years) were examined
in a prospective study before, 1 month and 3 months after ETE. At each
time intraocular pressure, mean deviation of scotomas (30-II-programm,
Humphrey Field Analyzer), ocular pulse amplitude, ocular pulse volume
and pulsatile ocular blood flow (OBF) were compared. For statistical analysis
the t-test for paired samples was used.
Results: 1 month after ETE intraocular pressure dropped significantly
from 22+/-0.29 mmHg to 16.56+/-3.18 mmHg (p=0.001). Also after 3 months
there was a signifikant reduction to 16.04+/-2.7 mmHg (p=0.001). The average
number of antiglaucomatous eye drops could be reduced from 2.7 to 0.4
after 1 month and to 0.6 after 3 months. After ETE the mean deviation
of scotomas decreased from initial -13.69+/-8.89 dB to -12.46+/- 8.68
dB after 1 month (p=0.001) and to -12.55+/-9.16 dB after 3 months (p=0.02).
Ocular pulse amplitude, ocular pulse volume and pulsatile ocular blood
flow showed to be constant 1 and 3 months after ETE (p>0.05).
Conclusion: 1 and 3 months after ETE we could observe a significant
reduction of intraocular pressure and a significant decrease of glaucomatous
scotomas. However, hemodynamic parameters remained constant.