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Impressum
The Influence of Healon5® versus Viscoat® on the Endothelial Cell Count after Cataract Surgery.
Lehrer I. E., Tetz M. R., Anders N., Nimsgern C., Schmidt S.
Department of Ophthalmology Charité, Humboldt-University Berlin, Germany
Objective: Ocular viscoelastic devices (OVDs) are well established
in cataract surgery. Aim of this open prospective randomized patient and
observer masked study was to compare the effect of Healon5®, a new
highly viscous OVD, and Viscoat® on postoperative endothelial cell
loss, intraocular pressure (IOP) and laser flare.
Methods: 63 eyes of 63 patients undergoing routine phacoemulsification
followed by foldable IOL implantation were enrolled. Either Healon5®
or Viscoat® that tend to remain in the anterior segment during the
process of phacoemulsification was used according to a block-randomization
scheme. Endothelial cell counts were compared pre- and 3 months postoperatively.
IOP and laser flare measurements were taken 5 and 24 hours postoperatively.
Results: Endothelial cell loss differed between the two groups
with a relative change in endothelial cell density after 3 months: -4,1%
for the Healon5® group and -11,4% for the Viscoat® group. IOP
and laser flare values were not statistically significantly different.
Conclusion: Healon5® showed compared to Viscoat less endothelial
cell loss and seems to have protective properties for the corneal epithelium.