Abstract 99. Jahrestagung der DOG, 29. 9. - 2. 10. 01 im ICC, Berlin

Anmeldung zur Tagung
Allgemeiner Ablauf
   General overview
Wissenschaftliches Programm
   Scientific program
Frühstück mit Spezialisten
   Breakfast with specialists
   Social program
DOG Information
   DOG Information
Allgemeine Informationen
   General Information
   Index of Authors
   Registration fees

Neuroretinal Rim Shape and Regional Visibility of the Retinal Nerve Fiber Layer in South Indians

1Nestel A., 2George R., 2Thomas R., 3Muliyel J. P., 1Jonas J. B.

1Department of Ophthalmology, Faculty for Clinical Medicine Mannheim of the University Heidelberg; 2Department of Ophthalmology, Christian Medical College, Vellore, Tamil Nadu, Indien; 3Department of Community Health, Christian Medical College, Vellore, Tamil Nadu, Indien

Purpose: The neuroretinale rim is the intrapapillary equivalent of the optic nerve fibers, and by that, the most important intrapapillary parameter for the quantification of the retinal ganglion cell axons. Besides its size, it is the shape of the neuroretional rim which is of utmost importance for the early diagnosis of glaucomatous optic neuropathy. Since the morphology of the optic nerve head depends on the ethnic background, it was the purpose of the present study to evaluate the shape of the neuroretinal rim in a South Indian population. Additionally, the ophthalmoscopic visibility of the retinal nerve fiber layer as second parameter for the assessment of the optic nerve should be examined.
Patients and Methods: The study included 73 ophthalmologically unremarkable subjects living in a suburb of Vellore, Tamil Nadu, South India. The subjects were randomly chosen and asked to participate in a routine eye examination and in the study. All subjects were adults (age range, 35-65 years) and were part of a population based sample that had been investigated 5 years prior to the start of the present study. The subjects of the present study formed a randomly selected subgroup of subjects who were called for a follow-up examination. The study group was compared with a control group consisting of 50 Caucasian subjects. Color stereo optic disc photographs taken of all subjects included in the study were evaluated.
Results: The neuroretinal rim had a characteristic configuration. It was significantly (P<0.001) the widest at the inferior optic disc pole, followed by the superior disc pole, the nasal optic disc region, and it was thinnest in the temporal region of the optic disc. The shape of the neuroretinal rim thus fulfilled the "ISN´T" rule. The neuroretinal rim shape was independent (P>0.10) of the optic disc size, the area of the neuroretinal rim, the optic cup depth, the presence and size of zones alpha and beta of the parapapillary atrophy, age, right or left eye, gender and refractive error. Corresponding to the shape of the neuroretinal rim, the ophthalmoscopic visibility of the retinal nerve fiber layer was significantly (P<0.01) the best in the temporal inferior fundus region, followed by the temporal superior fundus region.
Conclusions: Thee neuroretinal rim shows in South Indians as well as in Caucasians a characteristic shape according to the "ISN´T" rule. This rim shape is independent of the ocular and general parameters mentioned above. Correspondingly, the ophthalmoscopic visibility of the retinal nerve fiber layer is better temporal inferiorly than temporal superiorly. These findings may be of importance for the diagnosis of glaucomatous optic nerve damage in Asiatic patients.

DOG HomepageZurück / Back