Anmeldung zur Tagung
Registration
Grußwort
Invitation
Themen
Topics
Allgemeiner Ablauf
General overview
Wissenschaftliches Programm
Scientific program
Kurse
Courses
Symposien
Symposiums
Frühstück mit Spezialisten
Breakfast with specialists
Arzthelferinnen-Fortbildung
Rahmenprogramm
Social program
DOG Information
DOG Information
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Ausstellerliste
Exhibitors
Sponsoren
Sponsors
Teilnahmegebühren
Registration fees
Impressum
Analysis of Peripapillary Retinal Nerve Fiber Layer Thickness by Means of Heidelberg Retina Tomograph (HRT)
1Schmidt E., 1Scheuerle A. F., 2Diehl M., 1Burk R. O. W.
1Department of Ophthalmology, University of Heidelberg, INF 400, D- 69120 Heidelberg, 2IWR, University of Heidelberg, INF 368, D-69120 Heidelberg
Objective: Using the standard software the evaluation of HRT tomographies
is based on topometric parameters of the optic disc. We investigated if
analysis of the peripapillary retinal nerve fiber layer thickness (RNFLT)
allows detection of glaucomatous damage.
Methods: A total of 40 eyes of 36 subjects were examined by HRT
(15°- scan). Groups were classified as 1) normal and 2) glaucoma by
static perimety, intraocular pressure and HRT-discriminant function analysis.
Mean age and refraction were equal in both of the two groups. We centered
circles with increasing diameter up to the 1,8-fold diameter of the optic
disc around the papilla and measured the mean height of contour line.
According to HRT-software the difference to the standard refernce plane
resulted in RNFLT that was plotted against the corresponding diameter
of contour line. We calculated mean gradient of the curve between 1) 1,0-
to 1,8-fold papillary diameter (area I) and 2) 1,4- to 1,8-fold diameter
(area II) of both groups.
Results: The mean gradient of RNFLT-profile of normal subjects
was 0,029 ± 0,05 in area I and -0,02 ± 0,03 in area II .
In glaucomatous patients mean gradient in area I was 0,23 ± 0,087
and 0,13 ± 0,076 in area II. Both of the two areas exhibited highly
significant differences (p<0,001) between normal and glaucomatous eyes
regarding the mean gradient of RNFLT-profile.
Conclusion: Glaucomatous eyes showed a significant different profile
of peripapillary RNFLT compared to the control group. The topometry of
the retinal surface of normal eyes demonstrated a slightly ascending and,
more peripherally, descending profile. In contrast the RNFLT profile around
the optic disc of an eye with glaucomatous disease is much steeper. This
can be easily observed during clinical routine of HRT measurments.