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Review on keratoprosthesis research, Experiments on the Aachen type keratoprosthesis
Schrage N., Langefeld S., von Fischern T., Kompa S., Drechsler H.
Universitätsklinikum der RWTH Aachen, Augenklinik
Reconstruction of a clear cornea is a major obstacle in chronic inflammatory
diseases of the anterior segment such as pemphigoid, Stevens Johnson Syndrome,
eye burns and chronic hypotony Syndrome, requiring long term silicone
oil endotamponade. In cases where corneal transplantation is not successful
surgery with keratoprotheses offers a possibility to regain some visual
acuity and to stabilise the integrity of the eye The common aim in evolution
of keratoprotheses is to develop an artificial cornea. By means of new
techniques such as "Tissue engineering" this horizon seem to
open as real replacement of corneal transplants by regrowing corneas.
The question rises whether keratoprothesis development is a contemporary
tool of rehabilitation. Do we need in future the polymeric keratoprstheses?
Which risks have the current keratoprostheses and what can we expect as
surgical perspectives within the near future? Starting from own experiments
and in comparison to other researchers we offer an actual survey of keratoprosthesis
development.