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Impressum
The determination of retinal oxygen saturation in patients with low tension glaucoma
1Scibor M., 1Michelson G., 2Schweitzer D., 2Hammer M., 1Harazny J.
1Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Erlangen; 2Augenklinik mit Poliklinik, Universität Jena, Jena
Purpose: The measurement of oxygen saturation in arterioles and
venoles in patients with low tension glaucoma
Method: The determination of oxygen saturation was performed using
the imaging spectrometer, developed in Jena. Different extinction spectra
of hemoglobin and oxyhemoglobin create the basis for the non-invasive
estimation of the oxygen saturation. The measurements of the reflectance
spectra were performed in a wavelength range from 400 nm to 700 nm. The
retinal oxygen saturation was measured with an entrance slit of 1.5 mm,
spectral resolution of Dl < 2m, and local resolution Ds < 20µm.
We measured 72 eyes of healthy persons and 62 eyes of patients with low
tension glaucoma.
Results: In patients with low tension glaucoma the oxygen saturation
was in average 89% in retinal arterioles and 55% in retinal veins. In
normals the oxygen saturation was in average 93% in retinal arterioles
and 55% in retinal venoles.
Conclusions: In eyes with low tension glaucoma we found a significant
decrease of oxygen saturation in retinal arterioles (P=0.004) and no significant
difference in the mean oxygen saturation of retinal veins(P=0.417).