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Impressum
Reading ability after photodynamic therapy (PDT) for age-related macular degeneration (ARMD) and for high myopia
1Thölen A., 2Bernasconi P., 1Fierz A., 1Messmer E., Messmer E. M.
1Augenklinik Stadtspital Triemli Zürich, 2Augenklinik Samedan
Objective: Results published to date about photodynamic therapy
with verteporfin only consider distance visual acuity and contrast sensitivity.
The goal of this ongoing study is to follow the changes in reading ability
after PDT in patients with ARMD or high myopia.
Methods: A total of 93 patients with ARMD or high myopia with predominantly
classic subfoveal choroidal neovascular membranes (CNV) were treated with
PDT. 38 patients with ARMD were followed for a minimum of six months.
Among the high myopes, 16 were followed for six months, and 75% of these
for nine months. In all patients, follow-up included testing near vision
with a conventional reading card and the magnification required for reading.
PDT was repeated every three months if required, according to the usual
guidelines.
Results: Before treatment, the average reading acuity for the group
of 38 patients with ARMD was between 20/200 and 20/100. Average magnification
was between 2.5x and 3.2x. After six months, the mean magnification was
3.2x. 68% initially required a magnification of </= 3.2x. After six
months, 55% required a magnification of </= 3.2x. The group of 16 highly
myopic patients initially had a mean reading acuity of 20/100 and required
a mean magnification of 2.5x. Six months later, magnification was between
2.0x and 2.5x. Before treatment, 62% required a magnification of </=
3.2x. After six months, 75% required a magnification of </= 3.2x. The
results at nine months were comparable.
Conclusion: Six months into this study, 55% of ARMD patients treated
with PDT maintained their ability to read with a magnification of </=
3.2x. Patients with high myopia showed a slight tendency towards improved
reading ability at six and nine months. These data are the interim results
of an ongoing study.