Abstract 99. Jahrestagung der DOG, 29. 9. - 2. 10. 01 im ICC, Berlin

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Presentation of the clinical study "The effect of glucocorticoids and diclofenac/indomethacin for the anterior chamber inflammation response after phacoemulsification cataract surgery with intraocular lens implantation"

Wabra A., Hehl E.-M., Beck R., Guthoff R., Drewelow B.

Universität Rostock, Universitätsaugenklinik

In July 2000 we started with the clinical study "The effect of glucocorticoids and diclofenac/indomethacin for the anterior chamber inflammation response after phacoemulsification cataract-surgery with intraocular lens implantation". We recruit patients from the region of rostock with indication for cataractsurgery, which dont have any difficult eye- or general disease with an influence of the aqueous humor-barrier or the general cure. The aim of this study is the evaluation of the efficiency and the optimation for use of local topical antiphlogistics with different concentrations and present forms. As our main aim we definit the regression of the anterior chamber inflammation, which we measure using Kowa FM 500 laser-flare-meter, to baseline before operation. Second criterias are the regression of the corneal swelling to baseline, elevation of intraocular tension, parameter of individual compatibility and the concentration of active agent in aqueous humor.




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