Wakili N., Jünemann A., Horn F., Dzialach M., Korth M.

Department of Ophthalmology, University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen

Introduction: In the context of the Erlangen Glaucoma Registry (EGR) the value of blue-on-yellow-perimetry for early diagnosis of glaucomatous visual field defects in comparison to white-on-white-perimetry with the Octopus 101 was analysed.
Methods: In 28 normals, 22 patients with ocular hypertension (OHT) and 28 patients with preperimetric open angle glaucoma (preOAG) of the EGR a blueon- yellow-perimetry (BYP, Octopus 101, G2) and a white-on-white-perimetry (WWP, Octopus 101, G1) were performed. All of them were trained in WWP. The BYP was repeated after 6 weeks. The mean defect of the second BYP (BYMD) and the WWP (MD) were analyzed with the t-test. The BYMD of the first and second BYP was compared with the Wilcoxon-t-test.
Results: In the OHT the BYMD was significantly worse (-0,35±2,28dB, p<0,01), the MD significantly better (-0,03±0,74dB, p<0,01) than in the normals (BGMD -2,65±2,91dB/MD 0,89±1,18dB). In the preOAG the BYMD was significantly worse (0,49±3,67dB p<0,01). The MD (0,76±1,28dB,p>0,5) showed no significant difference in comparison to the normals. In all study groups the BYMD revealed a greater variation than the MD. There was no significant difference in BYMD between the first and second BYP (p>0.1).
Conclusion: This study confirms the usefulness of blue-on-yellow-perimetry in detecting early functional glaucomatous damage using Octopus 101. As shown by other studies, there was a greater interindividual variability and a good reproducibility in comparison to white-on-white-perimetry. (SFB 539)

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