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Impressum
Grid-lasercoagulation of soft drusen in age-related maculopathy
Witte K., Eickhorst M., Marx A., Behling T., Hoffmann K., Wiechens B.
Dept. of Ophthalmology, Klinikum Hannover, Haltenhoffstr. 41, D-30167 Hannover
Background: Soft drusen may play a role in the etiology of choroidal
neovascularization (CNV) in age-related macular degeneration. The staudy
was performed to investigate the regression rate of soft drusen after
gridlasercoagulation.
Materials and methods: A total of 578 eyes were treated by gridlasercoagulation.
Laser spots were applied according to the following parameters: exposure
time: 0.07 - 0.1 sec., energy: 70 - 120 mW, spot size:100 µm, wave
length: 532 nm. With this technique a mild, hardly visible laser spot
was achieved. Follow-up examinations were performed after 3, 6, 12, and
18 months.
Results: 242 of 578 eyes could be regularly followed within this
study. Partial or total regression of the drusen were observed in 84 %
of cases. The course of the visual acuity correlated to the number of
drusen. Complications attributable to laser treatment were not observed.
In some cases temporary visual disturbances after lasercoagulation regressed
after a few days or weeks. Development of CNV occurred in 8 of 242 cases
(3.3 %).
Conclusion: In age-related maculopathy regression of soft drusen
can be achieved by mild laser coagulation. Prospecive studies have to
be performed to further elucidate a potential benefit of mild laser coagulation
of soft drusen and ist influence on the incidence of CNV.