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Interaction of Foveal Topography (HRT), Centre of Fixation (SLO) and Quality of Ophthalmic Wave-front Sensing

Scheuerle A. F., Specht H., Bültmann S., Rohrschneider K.,
Ruprecht-Karls-Universität Heidelberg, Universitäts-Augenklinik (Heidelberg)

Purpose: The common used aberrometry systems follow the principles of Tscherning and Hartmann-Shack. The basis of data acquisition is a defined pattern projected onto the fovea and the analysis of the reflected pattern. Tscherning Aberrometry Systems illuminate a fovea area of about 1mm in diameter, Hartmann-Shack uses an area of 10µm for reflection.
Methods: We investigated the retinal profile of the macular region of 20 healthy and slightly myopic (to -5,0 sph) eyes by means of Heidelberg Retina Topograph (HRT II). Topographic data of the foveal surface consisted of three series with 16 images per millimeter depth. Horizontal resolution was 384² Pixel at an 15° angle. All subjects also performed a funduscontrolled mikroperimetry with a scanning-laser-ophthalmoscope (SLO), to correlate the anatomy of the fovea the centre of fixation.
Results: The topographies centered around the foveola often did not show rotational symmetry. We discovered differences in height up to 10µm. Two subjects showed gradients of up to 12° in the temporal direction. In the majority of subjects the anatomical-geometric centre was not identical with the centre of fixation.
Conclusions: The topography of the human fovea and the centre of fixation do not correspond with the centre of an ideal parabolic mirror. This leads to the conclusion that the reflection of a defined pattern will be added with non neglect errors which have to be considered in the calculation of an exact wave aberration map.

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