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Short-wavelength Automated Perimetry in Age-related Maculopathy: Follow-up Examination
Lichtenberg K., Remky A., Plange N., Arend O.,
RWTH Aachen, Universitätsaugenklinik (Aachen)
Background: In age-related maculopathy short-wavelength sensitive (SWS) cone mediated sensitivity is reduced. This study was performed to investigate the correlation of functional changes to visual outcome.
Methods: 74 patients with age- related maculopathy (mean age 71±6 years) were included. Follow-up examination was performed 24±12 months after baseline (fundus photograph, blue-on-yellow-perimetry: Humphrey field analyzer program 10-2).
Results: In 48 eyes (65%) fundus changes remained stable and no visual loss was observed (ARM). 26 eyes (35%) had a significant visual loss due to choroidal neovascularization or atrophy(AMD). At baseline these groups did not differ in presence of soft drusen or focal hyperpigmentation and in visual acuity (ARM: logMAR 0.11±0.12, AMD: 0.14±0.11, p = 0.25). A significant difference was found for the mean sensitivity assessed with blue-on-yellow perimetry at baseline between the both groups (ARM: 22.0±4.3 dB; AMD: 17.3±6.0 dB; p = 0.0004).
Conclusions: Short-wavelength sensitive (SWS) cone mediated sensitivity in correlates in age-related maculopathy and seems to be an important prognostic factor.