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Goniometry with Slit-lamp-adapted Optical Coherence Tomography
Karandish A., Wirbelauer C., Häberle H., Pham D.-T.,
Vivantes Klinikum Neukölln, Klinik für Augenheilkunde (Berlin)
Purpose: The visualisation of the anterior chamber angle is an important part of diagnosis in patients with glaucoma. Optical coherence tomography (OCT) was used to study the angle thus in a clinical setting.
Methods: 50 eyes of 50 patients suffering from primary chronic open glaucoma (n=27), age related cataract (n=15) and patients with angle-closure glaucoma (n=8) were studied with OCT. The angle width was measured by OCT in degree [°] and the angle opening distance (AOD) metrically [µm]. The anterior chamber angle in gonioscopy was graded using the Spaeth/Shaffer grading system.
Results: The mean angle width was 38±14,4° (0-70°) and the mean AOD was 562±230µm (0-1295µm). There was statistically significant correlation (r=0,89, p<0,001) between angle width measured by OCT and the gonioscopy foundings. The reproducibility was high with ±2,3° (7,4%) for the angle with and ±46µm (10%) for the AOD.
Conclusions: The two dimensional visualisation of the anterior chamber angle and its assesment with slit-lamp-adapted OCT is simple, fast and without contact. Our results suggest that OCT has potential applications in evaluating patients with glaucoma.