Aktuelle Tagungsinformationen
News and Updates
Anmeldung zur Tagung
Registration
Hotelbuchung
Hotel Registration
Grußwort
Welcome address
Beteiligte Gesellschaften
Societies involved
Eröffnung des Kongresses
Opening Ceremony
Preise
Awards
Wissenschaftliches Programm
Scientific program
Posterpräsentationen
Poster Presentation
Kurse
Courses
Begleitende Veranstaltungen
Collateral Events
Rahmenprogramm
Social program
Jubiläumsparty
Jubilee Party
DOG Information
DOG Information
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Ausstellerliste
Exhibitors
Sponsoren
Sponsors
Teilnahmegebühren
Registration fees
Impressum
DOG Homepage
Transplantation of Autologous Retinal Pigmentepithelial Cells in Age-related Macular Degeneration with Foveal Choroidal Neovascularisation - Results of 70 Cases
1Binder S., 2Krebs I., 3Feichtinger H., 2Abri A., 4Hilgers R.-D., 2Kellner L., 2Jahn C., 2Stolba U., 2Assadoullina A., 2Stanzel B.,
1Ludwig-Boltzmann-Institut, Retinologie und biomikroskopische Laserchirurgie (Wien)
2Ludwig-Boltzmann-Institut für Retinologie und biomikroskopische Laserchirurgie (Wien)
3Krankenanstalt Rudolf-Stiftung, Institut für Pathologie und Bakteriologie (Wien)
4RWTH Aachen, Institut für Medizinische Statistik (Aachen)
Purpose: To present the results of a series of 70 cases with f CNV related to AMD were subretinal membrane excision was combined with simultaneous transplantation of autologous RPE cells.
Material and Methods: 70 eyes of 68 patients with AMD and fCNV underwent subretinal surgery with simultaneous transplantation of autologous RPE cells, a method already described in the pilot study. Examinations were performed in 3 months intervals and included best corrected visual acuity for far and near, fluorescein- and indocyaningreen -angiografie, multifokale elekroretinografie (mERG) and optical coherence tomographiy (OCT). Seven eyes, were only membrane excision was performed, served as controls.
Results: After a medium observation time in 64 cases of 18 months (6-36 months) visual improvement of 2 or more lines was found in the cases with transplantation ( 57) in 43.8.% (25 /57), remained unchanged (±1 line) in 48.7% (38/57) and decreased 2lines or ore in 7.5%(4/57). Multifokal ERGs showed the highest medium potential after 3 months and remained higher than the preoperative values thereafter. A recurrent membrane growth was observed in 2 eyes (4%) , one after 6 months one after 2 years.
Conclusions: These results suggest that transplantation of autologous RPE might be a treatment option for patients with fCNV related to AMD. Recurrent membranes were observed rarely.