Aktuelle Tagungsinformationen
News and Updates
Anmeldung zur Tagung
Registration
Hotelbuchung
Hotel Registration
Grußwort
Welcome address
Beteiligte Gesellschaften
Societies involved
Eröffnung des Kongresses
Opening Ceremony
Preise
Awards
Wissenschaftliches Programm
Scientific program
Posterpräsentationen
Poster Presentation
Kurse
Courses
Begleitende Veranstaltungen
Collateral Events
Rahmenprogramm
Social program
Jubiläumsparty
Jubilee Party
DOG Information
DOG Information
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Ausstellerliste
Exhibitors
Sponsoren
Sponsors
Teilnahmegebühren
Registration fees
Impressum
DOG Homepage
In Vivo Con-focal Microscopic Examinations of Corneas in Diabetic Patients
Imre L., Papp A., Nagymihály A.,
Medical University Semmelweis, 1st Department of Ophthalmology (Budapest)
Background: The purpose of the present study was to investigate the in vivo corneal morphology of diabetic patients with the help of confocal microscopy, and to compare it with normal controls.
Methodes: We examined 30 eyes of 15 patients (11/15 Type II diabetes, 4/15 Type I diabetes) before argon laser photocagulation (mean age 67±8.2 years). 30 eyes of 15 healthy patients served as control (mean age 71±7,6 years). Our investigations was performed with the Tomey Confoscan slit-scanning type equipment. We evaluated the epithelial layers, the subepithelial nerves, the keratocytes of the anterior and posterior stroma, and the endothelial cell layer.
Results: Examining the epithelial cell layers we did not find any significant alteration in the cellform or in the cellcount. In four cases of the diabetic group (13.3%) abnormal subepithelial nerves were observed, while no alteration of the nerves was found in the control group. We did not find any significant change in the number of the anterior or the posterior keratocytes. The density of the endothelial cell layer was 2615±352 cell/mm2 in the diabetic group and 2750±412 cell/mm2 in the control group (P<0,05). We observed increased polymegethism in the diabetic group (CvDiab 0,46, CVcontr 0,35, P<0,05).
Conclusions: We could find pathologic changes only in the course of the subepithelial nerves and in the endothelial cell layer of the diabetic group. The possible connection between the abnormality of the subepithelial nerves and the coexsisting polineuropathy has further to investigate.