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Role of Fluorescein Angiography (FAG) in the Diagnosis of Choroidal Melanoblastoma
Zykov O.,
IRTC Eye Microsurgery, Ekaterinburg Center (Ekaterinburg)
Aim: to define the meaning of angiographic signs in diagnostics of choroidal melanoblastoma.
Patients and Methods: Videoangiography was performed in 20 patients (20 eyes) with clinical and echographic signs of melanoblastoma and in 9 eyes with choroidal nevus.
Results: In 18 cases of suspected melanoblastoma both angiographic signs (focal hyperfluorescence and proper vessels of the neoplasm) were disclosed. In 2 cases only proper vessels were seen due to blockade of hyperfluorescence with pigment. 17 eyes were enucleated and hystologic investigation approved the diagnosis of melanoblastoma. In 2 cases brachythepapy was performed and one patient refused from enucleation. In eyes with choroidal nevus hypofluorescence of the neoplasm was seen in 7 cases and weak hyperfluorescence without proper vessels in 2 cases. These patients were taken for follow-up.
Conclusions: Complex diagnostics including FAG must be used in diagnostics of choroidal melanoblastoma. In early stages of the disease FAG gives a possibility for timely organ-preserving treatment. Focal hyperfluorescence and proper vessels are reliable signs of melanoblastoma while hypofluorescence is characteristic for choroidal nevus.