Programm & Abstracts                 "Innovationen in der Augenheilkunde"

Aktuelle Tagungsinformationen
   News and Updates

Anmeldung zur Tagung
   Registration
Hotelbuchung
   Hotel Registration
Grußwort
   Welcome address
Beteiligte Gesellschaften
   Societies involved
Eröffnung des Kongresses
   Opening Ceremony
Preise
   Awards
Wissenschaftliches Programm
   Scientific program
Posterpräsentationen
   Poster Presentation
Kurse
   Courses
Begleitende Veranstaltungen
   Collateral Events
Rahmenprogramm
   Social program
Jubiläumsparty
   Jubilee Party
DOG Information
   DOG Information
Allgemeine Informationen
   General Information
Autorenindex
   Index of Authors
Ausstellerliste
   Exhibitors
Sponsoren
   Sponsors
Teilnahmegebühren
   Registration fees
Impressum



DOG Homepage

Increased Levels of Zinc in Human Cataractous Lenses

1Dawczynski J., 2Blum M., 3Winnefeld K., 1Strobel J.,
1Friedrich-Schiller-Universität Jena, Klinik für Augenheilkunde (Jena)
2HELIOS-Klinikum Erfurt , Klinik für Augenheilkunde (Erfurt)
3Friedrich-Schiller-Universität Jena, Universitätsklinikum, Institut für Klinische Chemie und Laboratoriumsmedizin (Jena)

Purpose: To examine the zinc content of human lenses in different types of cataract and to investigate the possible influence of diabetes on the zinc content of the lens.
Method: 63 human lenses (31 corticonuclear cataracts and 32 mature cataracts with a mean age of 71.2±15.1 vs. 73.9±10.8 years; 44 non-diabetics vs. 19 diabetics) were investigated by atomic absorption spectroscopy.
Results: Zinc content of human lenses was significantly increased in mature cataracts compared to corticonuclear cataracts (0.52±0.38 vs. 0.32±0.18 µmol/g dry mass, p=0.011). Furthermore, a significant increase of the lens zinc content could be observed with increasing lens coloration (light brown 0.34±0.19 vs. dark brown 0.53±0.33 µmol/g dry mass, p=0.031). Diabetic patients seem to have increased zinc contents in the lens compared to non-diabetic subjects (0.45±0.41 vs. 0.40±0.24).
Conclusions: These data suggest a possible influence of the lens zinc content on the development of lens opacification. Especially advanced forms of cataract and dark-brown colored lenses show significantly increased zinc content.

Zurück/Back