Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

   Hotel Registration
   Welcome address
Beteiligte Gesellschaften
   Societies involved
DOG Information
   DOG Information
Eröffnung des Kongresses
   Opening Ceremony
Ablauf der Tagung 2003
   General overview of congress
Lageplan der Räumlichkeiten
   Map of Congress Center
Wissenschaftliche Themen
   Scientific topics
Wissenschaftliches Programm
   Scientific program
   Poster Presentation
Begleitende Veranstaltungen
   Accompanying program
   Working sessions
   Social program
Allgemeine Informationen
   General Information
   Index of Authors
   Commercial exhibitors

DOG Homepage


LASIK-induced Changes on Central Corneal Thickness and Intraocular Pressure in Enucleated Porcine Globes

Feltgen N., Müller A., Funk J.
Dept. of Ophthalmology, Freiburg University 

Purpose: The intraocular pressure (IOP) in LASIK-treated eyes is lower as compared to preopertive values. We were interested if this difference is caused by changes in the central corneal thicknes (CCT).
Method: 80 freshly enucleated porcine globes were grouped as follows: group I: LASIK treated (n=20); group II: flap without LASIK (n=20); group III: control (n=40). In all eyes two different levels of IOP were measured (a: 10 and b: 18 mmHg). LASIK was performed by an excimer laser (193 nm). We tried to ablate between 100 and 211 µm of corneal tissue. The flap was cut with the Hansatome microkeratome. Before and after treatment the IOP was measured directly with an intraocular device and applanatory with the Tonopen and the Perkins tonometer. CCT was determined with an ultrasonic pachymeter. All eyes were examined histologically.
Results: Measurement with the Perkins tonometer often failed. Agreement between tonopen and directly measured IOP was very high in the controls (group III) and high in the flap eyes (group II). After LASIK the difference of IOP values (dL) between tonopen and direct measurement increased. At the level (a) dL was –0.8 mmHg, at the level (b) dL was –3,05 mmHg.
Conclusions: 1) Perkins measurement often failed in LASIK treated enucleated porcine eyes. However, we found an agreement between tonopen and directly measured IOP. In human eyes tonopen coul

Zurück | Back