Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Selenium and Zink in Blood of Patients with Acute or Chronic Uveitis

Dawczynski J.1, Winnefeld K.2, Strobel J.1
1Dept. of Ophthalmology, University Hospital Jena; 2Institute for Clinical Chemistry, University Hospital Jena

Purpose: Patients with chronic inflammation often show changes in selenium and zinc blood concentration. This study aimed to investigate the blood concentrations of selenium and zinc in patients with acute and chronic uveitis.
Method: Overal 23 patien (13 female and 11 male) with acute or chronic uveitis were included in this study. The mean age was 47.2 years. Selenium and zink measurements were performed by atomic absorption spectroscopy.
Results: Patients with acute uveitis showed nearly normal selenium and zink blood levels. However, patients with chronic uveitis showed sharply reduced reduced selenium and zinc concentrations in the blood. Furthermore, there was an decrease of these elements with increasing age of the patients. There was no sex dependency.
Conclusions: Especially patients with chronic uveitis showed legible reduced selenium concentrations in the blood. Further studies should show if there are any positive effects of a therapeutic selenium and zinc administration in patients with chronic uveitis.


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