Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Central Corneal Dermoid

Dithmar S.
Dept. of Ophthalmology, University of Heidelberg

Purpose: Dermoids are choristomatous malformations that often occur in the ocular region. Dermoids of the orbit are usually cystic whereas those that occur in the conjunctiva or the limbus are solid. Pure corneal dermoids are relatively rare.
Method: A 3-months-old boy was referred because of a whitish-yellow lesion of his left central cornea which had been noted since birth and which covered the pupil entirely. The round lesion was slightly eccentric and was supplied by blood vessels from the nasal portion of the bulbar conjunctiva. A lamellar keratoplasty was performed.
Results: Histologic examination revealed connective tissue covered by mildly keratinized stratified squamous epithelium. The lesion contained hair follicles and sebaceous glands. Bowman´s membrane was absent.
Conclusions: Epibulbar dermoids are most commonly found unilaterally in the inferotemporal quadrant at the limbus. Pure corneal dermoids are rare and can cause dense amblyopia. The here presented case has the typical histologic signs of a dermoid. Corneal dermoid can extend through the full thickness of the cornea and a penetrating keratoplasty may be necessary.


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