Hotelbuchung
Hotel Registration
Grußwort
Welcome address
Beteiligte Gesellschaften
Societies involved
DOG Information
DOG Information
Eröffnung des Kongresses
Opening Ceremony
Preise
Awards
Ablauf der Tagung 2003
General overview of congress
Lageplan der Räumlichkeiten
Map of Congress Center
Wissenschaftliche Themen
Scientific topics
Symposien
Symposia
Wissenschaftliches Programm
Scientific program
Posterpräsentationen
Poster Presentation
Kurse
Courses
Begleitende Veranstaltungen
Accompanying program
Arbeitssitzungen
Working sessions
Rahmenprogramm
Social program
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Industrieaussteller
Commercial exhibitors
Sponsoren
Sponsors
Impressum
DOG Homepage
Abstract
Abstract
Photodynamic Therapy for Circumscribed Choroidal Hemangioma Clinical Findings and Functional Outcome
Jurklies B., Anastassiou G., Ortmans S., Schüler A., Schilling H., Bornfeld N.
Universitäts-Augenklinik, Essen
Purpose: To investigate the efficacy and to document the functional outcome of photodynamic therapy (PDT) with Verteporfin in patients with choroidal hemangioma.
Method: 22 patients with symptomatic choroidal hemangioma were included in a non-randomised, prospective clinical investigation. To be included the following criteria had to be present: a decrease in visual function (visual acuity), visual symptoms (e.g. metamorphopsia) and a subretinal exudation involving the fovea in response to the symptomatic choroidal hemangioma. 4 patients had been pre-treated unsuccessfully (external beam irradiation and laser photocoagulation) prior to enrolment to the study. They have been included to exclude any effects of preliminary interventions on the functional outcome. Photodynamic therapy (PDT) was performed with Verteporfin at a concentration of 6 mg/qm body surface area and a light dose of 100 J/qcm at 692 nm.
Results: The mean follow-up time was 26 months (2-40 months). The mean number of treatment sessions was 2 (range 1- 5). Visual acuity improved by at least one line in 77 %, by at least two lines in 45 %, was stable in 18 % and decreased by one line in 5 % of the patients. Exudation was completely resolved in 95% of the cases. Regression of tumour height was documented in all 22 tumours. Patients did not show any significant improvement in functional o