|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Selective Anti-TNF-alpha Therapy of Chronic Therapy in Resistent Anterior Segment Inflammation
El-Shabrawi Y., Hermann J.
Purpose: Intraocular inflammatory diseases are a leading cause of visual impairment and blindness. Of those patients that develop recurrent or chronic anterior uveitis 23% will have a drop of vision below 20/50. The percentage of legally blind patients is 11%. Thus the treatment of these patients with chronic or recurrent uveitis still presents a quite a challenge, and additional treatment modalities are needed. Thus we tested the efficacy of selective anti-TNFa therapy in chronic inflammatory diseases of the anterior segment of the eye, non-responsive to or not tolerating standard antiinflammatory treatment consisting of a combined immunomodulatory and corticosteroid therapy.