Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Morphology of the Optic Nerve in Patients with Arterial Hypertension

Schröder A.1, Falk S.1, Wollstein J.2 , Meyer M.1, Erb C.1
1Department of Opthalmology, Medizinische Hochschule Hannover; 2Glaucoma Unit, Moorfields Eye Hospital, London/UK

Purpose: The aim of this study was to investigate the quantitative changes of the optic nerve morphology in patients with arterial hypertension using the Heidelberg Retina Tomograph II.
Method: Thirty-two patients (f:m=13:19; mean age 61±14 years) with arterial hypertension with damage in end-organs and 112 normal subjects as a control group (f:m=58:54; mean age 58±12 years) were included. Beside the ophthalmological examinations (visual acuity, refraction, intraocular-pressure, cup-disc-ratio, fundus examination) quantitative analysis of the optic nerve head parameters by scanning laser tomography was performed. Stereometric parameters (disc area, cup volume, rim area, rim volume, RNFL thickness, RNFL cross sectional area, cup-disc-ratio) were statistically compared with the Mann-Withney-U-Test.
Results: Hypertensive retinopathy grade I-II was found in 19 eyes of patients with arterial hypertension. However, in patients with arterial hypertension as well as in normal controls, the ophthalmological examination was within normal ranges. Statistic analysis showed no significant difference of all stereometric parameters of the HRT II between the patients with arterial hypertension and the control group (p>0.05).
Conclusions: Arterial hype


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