|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Lavasept® as Antiseptic Prophylaxis for Cataract-Surgery
Hansmann F.1, Kramer A.2, Ohgke H.3, Strobel H.4, Geerling G.1
Purpose: Endophthalmitis is the most serious complication of intraocular procedures. 1.25% polyvinylpyrrolidon-(PVP)-Iodine is routinely used for intraoperative antiseptic prophylaxis. This can result in allergic reactions. A 0.04% solution of polyhexamethylbiguanid (PHMB) in combination with Polyethylenglycol may be an effective antiseptic alternative (Lavasept®, Fresenius-Kabi, Germany) that would avoid these iodine-associated side effects. In addition this substance is bound by mucous membranes in sufficient bactericidal concentrations for up to 3 days. The aim of this study is to examine the antiseptic potential and local tolerability of preoperative 0.04% PHMB (equal to 0.02% Lavasept®) for intraocular surgery. After presenting pilot-data in 2002 we here report the results of the randomised controlled trial.