|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Changing Concepts in Glaucoma Therapy - Consequences from Recent Randomised Controlled Trials
For many years ophthalmologists believed that glaucoma is a disease of the optic nerve induced by elevated intraocular pressure. This concept advanced, following the recognition that the eye pressure did not need to be above the upper limit of normal, to one where glaucoma was seen as a disease of the optic nerve with elevated intraocular pressure as a risk factor. Even with this down-grading of the role of intraocular pressure, treatment for chronic glaucoma is still to reduce intraocular pressure. Until recently there had been no hard evidence to support this approach. In the last few years, however, there have been a number of thorough long term randomised controlled trials that demonstrated the beneficial effects of lowering intraocular pressure. These trials involved therapy versus placebo or different levels of intraocular pressure reduction.