Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Systemic Loa-Loa Filariasis and Ocular Affection – a Case report and Review of the Literature

Jaksche A.1, Wessels L.1, Martin S.2, Löffler K. U.1
1Universitätsaugenklinik, 2Institut für Medizinische Parasitologie der Universität, Universität Bonn

Purpose: Loa-Loa is a parasitic infection endemic in the tropical rain forests of Western, Central, and Eastern Africa. It is transferred by the Chrysops fly. Apart from involvement of the skin and systemic spread, it also can affect the eye, presenting as epiphora, eyelid edema, conjunctival injection and itching. Penetration into the anterior chamber and into retinal vessels has also been described. Within the last few years, there is more and more evidence for unclear eye-diseases to be caused by “exotic” pathogens. We herewith report another case of such an infection to underline the increasing importance and diagnostic relevance even of rare diseases.
Method: A 35-year-old female German patient presented at the University Eye Department with a suspected subconjunctival worm. She reported a recurrent left-sided retrobulbar pressure and swelling of skin and joints of hands and arms since a six-month-stay in central Africa 5 years ago. Ophthalmologic and rheumatologic examinations were carried out repeatedly but revealed no diagnostic results.
Results: Slit-lamp-examination confirmed the primary suspicion. After topical anaesthesia the worm was easily removed with forceps through a conjunctival cut. The differentiation of a “female Loa-Loa worm” was carri

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