Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Subacute Bilateral Blindness – An Extreme Side Symptom in Neuromyelitis Optica (Devic's Disease)

Ratajczak A. P., Gräf M., Kaufmann H.
Department of Ophthalmology, University of Giessen

Purpose: Neuromyelitis optica NMO (Devic's disease) is a rare syndrome within the complex of acquired demyelinization diseases of the central nervous system. NMO is characterised by mono- or bilateral optic neuritis combined with transverse lesions or vegetative disorders. It is discussed controversially as an own entity or a borderline variation of multiple sclerosis.
Case report: We report on a 35-year-old male patient referred to our hospital with an acute loss of vision (initially OS>OD). Looking with his left eye, he noticed “spots” in the central visual field. Simultaneously he felt “prickling sensations” at both soles and he suffered from paruria. Initially, he had been sent to a nearby neurological department where his vision suddenly decreased to perception of shapes and a few hours later, micturition became disturbed. Therefore, the patient was transferred to the Department of Neurology (University of Giessen) with parallel consultation of our outpatient department.
Method: We documented a sensitive transverse disorder (TH9) with a complete anuria, paresis and ascending paresthesia up to TH1. There was a bilateral optic disc edema with amaurotic pupils and extincted VEP. In the according spinal cord segments multiple myelitic lesions were detected by MRI in contrast to the normal cMRI of the brain. The cerebrospinal liquor showed slight signs of inflammati

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