|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Ex-vivo Expansion of Limbal Epithelial Stem Cells on Intact Amniotic Membrane as a New Therapeutic Approach in Recurrent Pterygium. A Case Report
Wüstemeyer H., Hernandez Galindo E. E., Steuhl K.-P., Meller D.
Purpose: The pterygium is a degenerative and hyperplastic disease which leads to a degeneration of Bowmans layer and disturbs the integrity and barrier function of the limbal epithelial cell population. Hence, a focal or partial limbal stem cell deficiency is induced. An increased UV exposure has been discussed as a crucial factor in the pathogenesis of the pterygium. A 73 year-old patient presented with a highly inflamed, twice recurrent pterygium of the left eye extending 6 hours of the nasal limbal circumference. Excision of pterygium had been performed twice unsuccessfully before. In the right eye a recurrence occurred after the first pterygium surgery.