Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Analysis of the Profile of the Peripapillary Nerve Fiber Layer with the Heidelberg Retina Tomograph (HRT)

Scheuerle A. F.1, Schmidt E.2, Burk R. O. W.3, Kruse F. E.1
1Department of Ophthalmology, University of Heidelberg
2Department of Ophthalmology, University of Dresden
3Department of Ophthalmology, City Hospital Bielefeld

Purpose: The Heidelberg Retina Tomograph (HRT) provides precise quantitative assessment of the living anatomy of the posterior pole. Up to now the three-dimensional data has mainly been used for the evaluation of glaucomatous optic discs. However little attention has been paid to the analysis the peripapillary retina. This study determines if the topography of the peripapillary nerve fiber layer changes during the course of glaucoma.
Method: 20 glaucomatous and 20 healthy eyes of 40 patients were investigated with the HRT. Normal and glaucomatous eyes were differentiated by static perimetry, IOP and discriminant function of the HRT software. Age and refraction were equally distributed among both groups. In analogy to the usual HRT assessment strategy the margin of the optic nerve head was outlined by a circle on 15°-scans. To analyze the peripapillary topography the circle around the disc was englarged from 100% to 180% in steps of 10%. The mean height of the conturline was measured along these circles.
Results: RNFL profiles of healthy eyes were relatively flat and showed a small elevation next to the optic disc. In contrast RNFL profiles of glaucoma patie

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