Endophthalmitis after Intravitreal Injection of Triamcinolone Acetonide
Kamppeter B. A., Jonas J. B., Kreissig I., Degenring R. F.
Dept. of Ophthalmology, Faculty for Clinical Medicine Mannheim, University Heidelberg
Purpose: To report the rate of infectious endophthalmitis and post-injection sterile intraocular inflammation after intravitreal injections of triamcinolone acetonide. Design. Interventional case series study.
Method: The study included 327 eyes which consecutively received intravitreal single or repeated injections of 25 mg of triamcinolone acetonide for treatment of edematous, neovascular, proliferative, or inflammatory ocular diseases. With topical anesthesia, the injection was performed in sterile conditions in the operation theater. The solvent agent was removed prior to the injection. Mean follow-up was 5.1 ± 4.7 months (range, one week 23.8 months).
Results: In none of the patients, an injection-related infectious endophthalmitis or a sterile post-injection intraocular inflammation was detected.
Conclusions: If the procedure is performed under sterile conditions in the operation theater, and if the solvent agent is removed, a post-injection endophthalmitis or post-injection intraocular inflammation may only rarely occur.
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