Relationship between Blood Flow Velocities in Retrobulbar Vessels and Intraocular Pressure in High-tension- and Normal-tension Glaucoma Patients
Matthiessen E. T., Zeitz O., Richard G., Klemm M.
Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Augenheilkunde, Hamburg, Germany
Purpose: Glaucomatous optic nerve damage is thought to be influenced by ocular perfusion. The aim of this prospective study was to investigate the relationship between the intraocular pressure and the retrobulbar blood flow velocities in high tension glaucoma patients and normal tension glaucoma patients. Colour Doppler imaging (CDI) was performed to measure the retrobulbar blood flow velocities.
Method: Data from 98 patients (196 eyes) including 69 high tension glaucoma patients (HTG) and 29 normal tension glaucoma patients (NTG) were evaluated prospectively. Patients coming originally to a multiday IOP analysis were subjected to the determination of retrobulbar blood flow velocities by CDI after the determination of the intraocular pressure (IOP) by the Goldmann applanation tonometry. The A. ophthalmica, the A. centralis retinae and the Aa. ciliares breves were investigated. As parameters of the retrobulbar blood flow velocities the systolic and diastolic peak flow, the pulsatility index, the mean blood flow velocities and the resistance index (RI) were evaluated. The statistical analysis contains the presentation of the correlation between the retrobulbar perfusion and the IOP as well the comparison between the collectives after IOP normalized blood flow velocities.
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