Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Hyaluronidase as an Adjuvans to the Peribulbar Injection during Cataract Surgery

Kersten D.1, Motschmann M.1, Duncker G. I. W.2
1Augenabteilung des Ohrekreis-Klinikums, Haldensleben; 2Augenklinik, Martin-Luther-Universität Halle-Wittenberg, Halle/Saale

Purpose: In a prospective study we wanted to evaluate the effect of adjuvant hyaluronidase to the peribulbar injection recording intraoperative pain sensation and circulatory parameters. Additionally, the akinetic effect, the intraoperative course as well the incidence of surgical complications was evaluated.
Method: 107 of 207 patients undergoing routine cataract surgery randomly received adjuvant hyaluronidase (150 IE) to their peribulbar injection. At 10 instances during surgery a subjective pain score was recorded. Blood pressure and pulse rate were monitored before, during and after surgery. The akinetic effect was determined by semiquantitative evaluation of remaining lid and globe motility. Further parameters were the necissity of additional injections, the amount of vitreous pressure, frequency of instrument changes, duration of surgery and the incidence of intraoperative complications. Fisher`s exact test and Wilcoxon test and variance analysis were applied for statistical evaluation.
Results: The patients with adjuvant hyaluronidase demonstrated a significantly lower pain score and a better akinetic effect. They required less additional injections and fewer instrument changes. Intraoperative vitreous pressure was less prominent and the duration of


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