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Abstract
Abstract
New Possibilities in Retinal Vessel Analysis
Kremmer S., Steuhl K.-P.
University Eye Hospital, Essen
Retinal vessel analysis is a new technique to assess their behaviour based on continuous diameter measurements. The Retinal Vessel Analyzer (RVA) is able to assess data on-line in relation to time and local position. Therefore, RVA enables not only measurements of vessel diameters in different diseases, e.g. glaucoma, diabetes, AMD but also vessel reactions after application of different therapeutical drugs. Additionally, vessel diameters can be examined at different kinds of provocation tests. As an example, typical results of glaucomatous disease are shown: the arterial response to blood pressure elevations (Bayliss effect) is changing from initial vessel dilation to vasoconstriction. At the beginning of a short artificial IOP elevation a vasoconstriction can be observed. After provocation follows a dilation for 10 15 minutes. Flicker light causes immediate vessel diameter dilations returning to initial diameters some seconds after provocation. These autoregulative and recovery capacities of the vessels are smaller and slower in glaucoma patients than in healthy persons.
The RVA enables new possibilities to detect disturbancies of autoregulative mechanisms of retinal vessels which can be helpful in diagnostics and therapy control of multiple diseases.