Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Methods of Computer-based Reconstruction of Optic Disk Morphology by Using Digitalized Stereo Fundus Photography

Marquardt D.1, v. Freyberg A.2, Goch G.2, Grehn F.1
1Dept. of Ophthalmology, Wuerzburg University; 2BIBA at Bremen University

Purpose: Papillary changes are a mayor criteria for detecting progression in glaucoma disease. Apart from confocal laser-scanning systems analog fundus photography has been used as long-term follow up method for decades. Computer based reconstruction of digitalized pictures can add some information on papilla morphology.
Method: We developed methods to reconstruct and analyze papilla morphology based on digitalized stereo fundus photography. By separating the intensity of different color bends we detected the rim of the papilla and other regions of interest automatically. This data is used for calculating two- and three-dimensional papilla morphology to see specific changes over time.
Results: Digitalized fundus photography shows specific intensity changes in different color bands. By extracting special color bands we were able to get better quality of certain processing features. This data allows to calculate two- and three-dimensional papilla morphology.
Conclusions: Color-frequency coded computer-based digitalization of analog fundus stereo photography allows better detection of specific structures within the papilla region. These are preconditions for suitable algorithms for computer-based reconstruction of the papilla and for


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