Central and Paracentral Corneal Pachymetry in Patients with Normal Tension Glaucoma and Ocular Hypertension
Jordan J. F. 1, Coburger S. 2, Dietlein T. S. 1, Krieglstein G. K. 1
1 University Eye Hospital, University of Cologne; 2 Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne
Purpose: The difference in the central corneal thickness of healthy people, patients with ocular hypertension (OHT) and patients with low-tension-glaucoma (LTG), as well as its influence on Goldmann applanation tonometry has been well documented in several clinical trials. In the present study, a possible correlation between the central corneal thickness and the corneal thickness of paracentral quadrants in patients with OHT and LTG was investigated.
Method: Central and paracentral corneal thickness was measured by opitcal pachymetry (Orbscan II). 11 patients with OHT and 14 patients with LTG were included into this study. T-test and ANCOVA were performed for statistical analysis. Statistical significance was assumed for p<0.05.
Results: The following data was obtained by Orbscan-pachymetry [µm]: (central, upper-, temporal-, nasal-, basal-paracentral quadrant): OHT-group 617.1 695.2 662.8 686.7 659.9. LTG-group 567.5 628.6 593 611.6 615.6. Corneal thickness of all four paracentral quadrants showed a significant difference between the OHT- and the LTG-group in both eyes. A difference / mean analysis of the central corneal thickness to each single paracentral quadrant sho
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