Diurnal Changes of Intraocular Pressure and Pulsatile Ocular Blood flow in Normal Pressure Glaucoma Patients
Mollenhauer K. A., Pillunat L. E., Koeller U. A., Boehm A. G., Mueller M. F.
Department of Ophthalmology, University of Dresden
Purpose: Aim of this study was to investigate the diurnal course ot intraocular pressure (IOP) and ocular perfusion in normal pressure glaucoma patients (NPG).
Method: In a prospective clinical trial 46 eyes of 24 patients with NPG (mean age 69.4±9.3y) were examined. IOP was measured by applanation tonometry and pulsastile ocular blood flow (pOBF) by the ocular blood flow system (OBF). In addition heart rate and blood pressure were taken. With both instruments diurnal measurements were performed every 4 hours for 2 days (4am and midnight measurements in supine position). Means for IOP and pOBF and the presence of maximum diurnal IOP at each time were calculated. Statistics were performed by univariate linear regression analysis and students t-test.
Results: Mean IOP was 14.42Zurück | Back